All Publications

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  1. Ashraf Ganjouei A, Romero-Hernandez F, Conroy PC, Miller P, Calthorpe L, Wang JJ, Lin J, Feng J, Kirkwood KS, Alseidi A, Sarin A, Adam MA. A Novel Machine Learning Approach to Predict Textbook Outcome in Colectomy. Dis Colon Rectum. 2023 Oct 10. View in PubMed
  2. Ashraf Ganjouei A, Romero-Hernandez F, Wang JJ, Casey M, Frye W, Hoffman D, Hirose K, Nakakura E, Corvera C, Maker AV, Kirkwood KS, Alseidi A, Adam MA. ASO Visual Abstract: A Machine-Learning Approach to Predict Postoperative Pancreatic Fistula after Pancreaticoduodenectomy Using only Preoperatively Known Data. Ann Surg Oncol. 2023 Nov; 30(12):7776-7777. View in PubMed
  3. Ashraf Ganjouei A, Romero-Hernandez F, Wang JJ, Casey M, Frye W, Hoffman D, Hirose K, Nakakura E, Corvera C, Maker AV, Kirkwood KS, Alseidi A, Adam MA. A Machine Learning Approach to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy Using Only Preoperatively Known Data. Ann Surg Oncol. 2023 Nov; 30(12):7738-7747. View in PubMed
  4. Calthorpe L, Romero-Hernandez F, Casey M, Nunez M, Conroy PC, Hirose K, Kim A, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA. ASO Visual Abstract: National Practice Patterns in Malignant Peritoneal Mesothelioma-Updates in Management and Survival. Ann Surg Oncol. 2023 Aug; 30(8):5131. View in PubMed
  5. Calthorpe L, Romero-Hernandez F, Casey M, Nunez M, Conroy PC, Hirose K, Kim A, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA. National Practice Patterns in Malignant Peritoneal Mesothelioma: Updates in Management and Survival. Ann Surg Oncol. 2023 Aug; 30(8):5119-5129. View in PubMed
  6. Lin JJ, Conroy PC, Romero-Hernandez F, Yilma M, Feng J, Hirose K, Nakakura E, Maker AV, Corvera C, Kirkwood K, Alseidi A, Adam MA. Hypertension Requiring Medication Use: a Silent Predictor of Poor Outcomes After Pancreaticoduodenectomy. J Gastrointest Surg. 2023 02; 27(2):328-336. View in PubMed
  7. Calthorpe L, Romero-Hernandez F, Miller P, Conroy PC, Hirose K, Kim A, Kirkwood K, Nakakura E, Corvera C, Maker AV, Alseidi A, Adam MA. Contemporary Trends in Malignant Peritoneal Mesothelioma: Incidence and Survival in the United States. Cancers (Basel). 2022 Dec 30; 15(1). View in PubMed
  8. Conroy PC, Mohamedaly S, Karimzada M, Brian R, Im C, Hernandez S, Roman S, Hirose K, Mukhtar R, Kirkwood K, O'Sullivan P, Alseidi A. Implementation, evaluation, and modification of a near-peer learning group in graduate surgical education. Am J Surg. 2023 03; 225(3):591-592. View in PubMed
  9. Miller PN, Romero-Hernandez F, Conroy P, Calthorpe L, Yilma M, Mohamedaly S, Kelly YM, Feng J, Hirose K, Kirkwood K, Maker AV, Corvera C, Nakakura E, Alseidi A, Adam MA. Hand-Assisted Versus Pure Minimally-Invasive Distal Pancreatectomy: Is There a Downside to Lending a Hand? World J Surg. 2023 03; 47(3):750-758. View in PubMed
  10. Romero-Hernandez F, Mohamedaly S, Miller P, Rodriguez N, Calthorpe L, Conroy PC, Ganjouei AA, Hirose K, Maker AV, Nakakura E, Corvera C, Kirkwood KS, Alseidi A, Adam MA. Minimally Invasive Distal Pancreatectomy Techniques: A Contemporary Analysis Exploring Trends, Similarities, and Differences to Open Surgery. Cancers (Basel). 2022 Nov 16; 14(22). View in PubMed
  11. Caiazza F, Conroy PC, Ivry SL, York T, Lin J, Hernandez S, Hoffmann TJ, Francis SS, Park WG, Yip-Schneider MT, Schmidt CM, Brand R, Craik CS, Kirkwood K. Accurate Identification of Mucinous Pancreatic Cystic Lesions Using Small-Volume Analytes. J Surg Res. 2023 04; 284:322-331. View in PubMed
  12. Suresh V, Byers K, Rajesh UC, Caiazza F, Zhu G, Craik CS, Kirkwood K, Davisson VJ, Sheik DA. Translation of a Protease Turnover Assay for Clinical Discrimination of Mucinous Pancreatic Cysts. Diagnostics (Basel). 2022 May 28; 12(6). View in PubMed
  13. Glencer AC, Lin JA, Trang K, Greenberg A, Kirkwood KS, Adam MA, Sarin A. Assessing the role of robotic proctectomy in obese patients: a contemporary NSQIP analysis. J Robot Surg. 2022 Dec; 16(6):1391-1399. View in PubMed
  14. Conroy PC, Calthorpe L, Lin JA, Mohamedaly S, Kim A, Hirose K, Nakakura E, Corvera C, Sosa JA, Sarin A, Kirkwood KS, Alseidi A, Adam MA. ASO Visual Abstract: Determining Hospital Volume Threshold for the Safety of Minimally Invasive Pancreaticoduodenectomy: A Contemporary Cutpoint Analysis. Ann Surg Oncol. 2022 Jan 15. View in PubMed
  15. Conroy PC, Calthorpe L, Lin JA, Mohamedaly S, Kim A, Hirose K, Nakakura E, Corvera C, Sosa JA, Sarin A, Kirkwood KS, Alseidi A, Adam MA. Determining Hospital Volume Threshold for Safety of Minimally Invasive Pancreaticoduodenectomy: A Contemporary Cutpoint Analysis. Ann Surg Oncol. 2022 Mar; 29(3):1566-1574. View in PubMed
  16. Lin JA, Im CJ, O'Sullivan P, Kirkwood KS, Cook AC. The surgical resident experience in serious illness communication: A qualitative needs assessment with proposed solutions. Am J Surg. 2021 Dec; 222(6):1126-1130. View in PubMed
  17. Thiruvengadam NR, Miranda J, Kim C, Behr S, Corvera C, Dai SC, Kirkwood K, Harris HW, Hirose K, Nakakura E, Ostroff JW, Kochman ML, Arain MA. Burden of Ionizing Radiation in the Diagnosis and Management of Necrotizing Pancreatitis. Clin Transl Gastroenterol. 2021 04 27; 12(5):e00347. View in PubMed
  18. Dittmar RL, Liu S, Tai MC, Rajapakshe K, Huang Y, Longton G, DeCapite C, Hurd MW, Paris PL, Kirkwood KS, Coarfa C, Maitra A, Brand RE, Killary AM, Sen S. Plasma miRNA Biomarkers in Limited Volume Samples for Detection of Early-stage Pancreatic Cancer. Cancer Prev Res (Phila). 2021 07; 14(7):729-740. View in PubMed
  19. Sharib J, Esserman L, Koay EJ, Maitra A, Shen Y, Kirkwood KS, Ozanne EM. Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective. Surgery. 2020 10; 168(4):601-609. View in PubMed
  20. Moroz A, Wang YH, Sharib JM, Wei J, Zhao N, Huang Y, Chen Z, Martinko AJ, Zhuo J, Lim SA, Zhang LH, Seo Y, Carlin S, Leung KK, Collisson EA, Kirkwood KS, Wells JA, Evans MJ. Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer. Clin Cancer Res. 2020 07 15; 26(14):3608-3615. View in PubMed
  21. Wisneski AD, Carter J, Nakakura EK, Posselt A, Rogers SJ, Cello JP, Arain M, Kirkwood KS, Hirose K, Stewart L, Corvera CU. Ampullary stenosis and choledocholithiasis post Roux-En-Y gastric bypass: challenges of biliary access and intervention. HPB (Oxford). 2020 10; 22(10):1496-1503. View in PubMed
  22. Cao CX, Sharib JM, Blanco AM, Goldberg D, Bracci P, Mukhtar RA, Esserman LJ, Kirkwood KS. Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study. J Am Coll Surg. 2020 01; 230(1):53-63.e1. View in PubMed
  23. Ivry SL, Knudsen GM, Caiazza F, Sharib JM, Jaradeh K, Ravalin M, O'Donoghue AJ, Kirkwood KS, Craik CS. The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts. Biol Chem. 2019 11 26; 400(12):1629-1638. View in PubMed
  24. Changala M, Laberge J, Kerlan R, Taylor A, Arain M, Kirkwood K. Managing Refractory Postoperative Fistulas as Chronic Wounds Using Video-Assisted Hydrodebridement (VAHD). J Gastrointest Surg. 2019 03; 23(3):608-612. View in PubMed
  25. Kim SS, Ko AH, Nakakura EK, Wang ZJ, Corvera CU, Harris HW, Kirkwood KS, Hirose R, Tempero MA, Kim GE. Comparison of Tumor Regression Grading of Residual Pancreatic Ductal Adenocarcinoma Following Neoadjuvant Chemotherapy Without Radiation: Would Fewer Tier-Stratification Be Favorable Toward Standardization? Am J Surg Pathol. 2019 03; 43(3):334-340. View in PubMed
  26. Sharib JM, Fonseca AL, Swords DS, Jaradeh K, Bracci PM, Firpo MA, Hatcher S, Scaife CL, Wang H, Kim GE, Mulvihill SJ, Maitra A, Koay EJ, Kirkwood KS. Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: Do the 2017 International Consensus Guidelines improve clinical decision making? Surgery. 2018 12; 164(6):1178-1184. View in PubMed
  27. Fonseca AL, Kirkwood K, Kim MP, Maitra A, Koay EJ. Intraductal Papillary Mucinous Neoplasms of the Pancreas: Current Understanding and Future Directions for Stratification of Malignancy Risk. Pancreas. 2018 03; 47(3):272-279. View in PubMed
  28. Kirkwood R, Damon L, Wang J, Hong E, Kirkwood K. Gangrenous cholecystitis: innovative laparoscopic techniques to facilitate subtotal fenestrating cholecystectomy when a critical view of safety cannot be achieved. Surg Endosc. 2017 12; 31(12):5258-5266. View in PubMed
  29. Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider MT, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim GE, O'Donoghue AJ, Kirkwood KS, Craik CS. Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts. Clin Cancer Res. 2017 Aug 15; 23(16):4865-4874. View in PubMed
  30. Sharib J, Kirkwood K. Early and accurate diagnosis of pancreatic cancer? Oncotarget. 2016 12 27; 7(52):85676-85677. View in PubMed
  31. Kim SS, Nakakura EK, Wang ZJ, Kim GE, Corvera CU, Harris HW, Kirkwood KS, Hirose R, Tempero MA, Ko AH. Preoperative FOLFIRINOX for borderline resectable pancreatic cancer: Is radiation necessary in the modern era of chemotherapy? J Surg Oncol. 2016 Oct; 114(5):587-596. View in PubMed
  32. Wang J, Paris PL, Chen J, Ngo V, Yao H, Frazier ML, Killary AM, Liu CG, Liang H, Mathy C, Bondada S, Kirkwood K, Sen S. Next generation sequencing of pancreatic cyst fluid microRNAs from low grade-benign and high grade-invasive lesions. Cancer Lett. 2015 Jan 28; 356(2 Pt B):404-9. View in PubMed
  33. Cattaruzza F, Amadesi S, Carlsson JF, Murphy JE, Lyo V, Kirkwood K, Cottrell GS, Bogyo M, Knecht W, Bunnett NW. Serine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants. Br J Pharmacol. 2014 Aug; 171(16):3814-26. View in PubMed
  34. Cattaruzza F, Johnson C, Leggit A, Grady E, Schenk AK, Cevikbas F, Cedron W, Bondada S, Kirkwood R, Malone B, Steinhoff M, Bunnett N, Kirkwood KS. Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice. Am J Physiol Gastrointest Liver Physiol. 2013 Jun 01; 304(11):G1002-12. View in PubMed
  35. Lee Char SJ, Hills NK, Lo B, Kirkwood KS. Informed consent for innovative surgery: a survey of patients and surgeons. Surgery. 2013 Apr; 153(4):473-80. View in PubMed
  36. Lyo V, Cattaruzza F, Kim TN, Walker AW, Paulick M, Cox D, Cloyd J, Buxbaum J, Ostroff J, Bogyo M, Grady EF, Bunnett NW, Kirkwood KS. Active cathepsins B, L, and S in murine and human pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2012 Oct 15; 303(8):G894-903. View in PubMed
  37. Minter RM, Angelos P, Coimbra R, Dale P, de Vera ME, Hardacre J, Hawkins W, Kirkwood K, Matthews JB, McLoughlin J, Peralta E, Schmidt M, Zhou W, Schwarze ML. Ethical management of conflict of interest: proposed standards for academic surgical societies. J Am Coll Surg. 2011 Nov; 213(5):677-82. View in PubMed
  38. Ceppa EP, Lyo V, Grady EF, Knecht W, Grahn S, Peterson A, Bunnett NW, Kirkwood KS, Cattaruzza F. Serine proteases mediate inflammatory pain in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2011 Jun; 300(6):G1033-42. View in PubMed
  39. Ceppa E, Cattaruzza F, Lyo V, Amadesi S, Pelayo JC, Poole DP, Vaksman N, Liedtke W, Cohen DM, Grady EF, Bunnett NW, Kirkwood KS. Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G556-71. View in PubMed
  40. Maa J, Carter JT, Kirkwood KS, Gosnell JE, Wang V, McDermott MW. Technique for placement of lumboperitoneal catheters using a combined laparoscopic procedure with the Seldinger micropuncture technique. J Am Coll Surg. 2008 Jul; 207(1):e5-7. View in PubMed
  41. Finzi L, Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housset C. MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder. Am J Pathol. 2006 Dec; 169(6):2031-41. View in PubMed
  42. Grahn SW, Alvarez J, Kirkwood K. Trends in laparoscopic splenectomy for massive splenomegaly. Arch Surg. 2006 Aug; 141(8):755-61; discussion 761-2. View in PubMed
  43. Wick EC, Pikios S, Grady EF, Kirkwood KS. Calcitonin gene-related peptide partially mediates nociception in acute experimental pancreatitis. Surgery. 2006 Feb; 139(2):197-201. View in PubMed
  44. Wick EC, Hoge SG, Grahn SW, Kim E, Divino LA, Grady EF, Bunnett NW, Kirkwood KS. Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2006 May; 290(5):G959-69. View in PubMed
  45. Day AL, Wick E, Jordan TH, Jaffray CE, Bunnett NW, Grady EF, Kirkwood KS. Neutral endopeptidase determines the severity of pancreatitis-associated lung injury. J Surg Res. 2005 Sep; 128(1):21-7. View in PubMed
  46. Hutter MM, Wick EC, Day AL, Maa J, Zerega EC, Richmond AC, Jordan TH, Grady EF, Mulvihill SJ, Bunnett NW, Kirkwood KS. Transient receptor potential vanilloid (TRPV-1) promotes neurogenic inflammation in the pancreas via activation of the neurokinin-1 receptor (NK-1R). Pancreas. 2005 Apr; 30(3):260-5. View in PubMed
  47. Lu EJ, Curet MJ, El-Sayed YY, Kirkwood KS. Medical versus surgical management of biliary tract disease in pregnancy. Am J Surg. 2004 Dec; 188(6):755-9. View in PubMed
  48. Lightner AM, Glasgow RE, Jordan TH, Krassner AD, Way LW, Mulvihill SJ, Kirkwood KS. Pancreatic resection in the elderly. J Am Coll Surg. 2004 May; 198(5):697-706. View in PubMed
  49. Kim EH, Hoge SG, Lightner AM, Grady EF, Coelho AM, Kirkwood KS. Activation of nociceptive neurons in T9 and T10 in cerulein pancreatitis. J Surg Res. 2004 Apr; 117(2):195-201. View in PubMed
  50. Kerlan RK, LaBerge JM, Wilson MW, Gordon RL, Kirkwood K, Sawhney R. SIR 2003 film panel case 5: massive hemorrhage from portal vein disruption. J Vasc Interv Radiol. 2003 Jun; 14(6):797-802. View in PubMed
  51. Abedin MZ, Narins SC, Park EH, Smith PR, Kirkwood KS. Lovastatin alters biliary lipid composition and dissolves gallstones: a long-term study in prairie dogs. Dig Dis Sci. 2002 Oct; 47(10):2192-210. View in PubMed
  52. Lightner AM, Jordan TH, Bunnett NW, Grady EF, Kirkwood KS. Recombinant human neutral endopeptidase ameliorates pancreatic elastase-induced lung injury. Surgery. 2002 Aug; 132(2):193-9. View in PubMed
  53. Lightner AM, Kirkwood KS. Pathophysiology of gallstone pancreatitis. Front Biosci. 2001 Oct 01; 6:E66-76. View in PubMed
  54. Kirkwood KS, Bunnett NW, Maa J, Castagliolo I, Liu B, Gerard N, Zacks J, Pothoulakis C, Grady EF. Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A. Am J Physiol Gastrointest Liver Physiol. 2001 Aug; 281(2):G544-51. View in PubMed
  55. Maa J, Grady EF, Kim EH, Yoshimi SK, Hutter MM, Bunnett NW, Kirkwood KS. NK-1 receptor desensitization and neutral endopeptidase terminate SP-induced pancreatic plasma extravasation. Am J Physiol Gastrointest Liver Physiol. 2000 Oct; 279(4):G726-32. View in PubMed
  56. Maa J, Grady EF, Yoshimi SK, Drasin TE, Kim EH, Hutter MM, Bunnett NW, Kirkwood KS. Substance P is a determinant of lethality in diet-induced hemorrhagic pancreatitis in mice. Surgery. 2000 Aug; 128(2):232-9. View in PubMed
  57. Grady EF, Yoshimi SK, Maa J, Valeroso D, Vartanian RK, Rahim S, Kim EH, Gerard C, Gerard N, Bunnett NW, Kirkwood KS. Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice. Br J Pharmacol. 2000 Jun; 130(3):505-12. View in PubMed
  58. Kirkwood KS, Kim EH, He XD, Calaustro EQ, Domush C, Yoshimi SK, Grady EF, Maa J, Bunnett NW, Debas HT. Substance P inhibits pancreatic exocrine secretion via a neural mechanism. Am J Physiol. 1999 08; 277(2):G314-20. View in PubMed
  59. Corvera CU, Kirkwood KS. Recent advances. General surgery. BMJ. 1997 Sep 06; 315(7108):586-9. View in PubMed
  60. Kirkwood KS, Khitin LM, Barwick KW. Prognostic indicators for cancer. Gastric cancer. Surg Oncol Clin N Am. 1997 Jul; 6(3):495-514. View in PubMed
  61. Figini M, Emanueli C, Grady EF, Kirkwood K, Payan DG, Ansel J, Gerard C, Geppetti P, Bunnett N. Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas. Am J Physiol. 1997 Apr; 272(4 Pt 1):G785-93. View in PubMed
  62. Kirkwood KS, Debas HT. Neuroendocrine tumors: common presentations of uncommon diseases. Compr Ther. 1995 Dec; 21(12):719-25. View in PubMed